The Indianapolis Colts will be one of the most interesting teams to watch in the 2021 NFL Draft, as they have the ability to go in one of several different directions with the No. 21 pick in this loaded draft class. The Colts need replacements at wide receiver and cornerback, but the exceptional talent at tight end, offensive tackle, and safety could help Chris Ballard shake up the latter half of the draft. While the top of the draft might be somewhat easy to predict, the Colts could completely turn the latter half of the draft on its head by making one unusual pick.